• Dosage and administration

Dosage and administration

Atopica for Dogs
dosing guide
Atopica for Cats
dosing guide

The label contains complete use information, including cautions and warnings.  Always read, understand and follow the label and use directions.

  • Initial 7mg/kg (0.07ml/kg) once daily until a good response is observed
  • Then taper the dose frequency according to clinical response: every other day, then twice weekly
  • The lowest effective frequency of dosing should be used to maintain the remission of clinical signs
  • In some cases the veterinarian can decide to dose every 3 to 4 days

The label contains complete use information, including cautions and warnings.  Always read, understand and follow the label and use directions.

The mean recommended dose of cyclosporine is 5 mg/kg body weight according to the tabulated dosage scheme.

Atopica dosage scheme:
Body weight of dogNumber of capsules given to obtain recommended dose
Atopica 10 mgAtopica 25 mgAtopica 50 mgAtopica 100 mg
2 to < 3 kg1 capsule
3 to < 4 kg2 capsules
4 to < 8 kg1 capsule
8 to < 15 kg1 capsule
15 to < 29 kg1 capsule
29 to < 36 kg3 capsules
36 to 55.9 kg2 capsules

Atopica will initially be given daily until a satisfactory clinical improvement is seen. This will generally be the case within 4 weeks, assuming accurate diagnosis and secondary infections and parasitism are controlled. [If no response is obtained within the first 8 weeks, the treatment should be stopped].

Once the clinical signs of atopic dermatitis are satisfactorily controlled, the preparation can then be given every other day as a maintenance dose. The veterinarian should perform a clinical assessment at regular intervals and adjust the frequency of administration to the clinical response obtained.

In some cases the veterinarian can decide to dose every 3 to 4 days.

Adjunct treatment (e.g. medicated shampoos, fatty acids) may be considered before reducing the dosing interval. Treatment may be stopped when the clinical signs are controlled.1 Upon recurrence of clinical signs, treatment should be resumed at daily dosing, and in certain cases repeated treatment courses may be required. 2

Atopica should be given at least 1 hour before or 2 hours after feeding. Insert the capsule directly into the dog’s mouth.

References: 1. Olivry T et al. JAVMA (2002);221:370-377. 2. Steffan J et al. JAVMA (2005);226:1855-1863. 3. Roberts ES et al. J Feline Med Surg (2016);1-9.